Chronobiology in Medicine

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Review Article

September 30, 2025

Role of Physical Rehabilitation in Managing Sleep Disorders in Neurologically Impaired Patients

Soumya Saswati Panigrahi, Srinivasan P, Deepak Kumar Barik, et al.

Chronobiol Med. 2025;7(3):114-127.

Sleep disorders are common among individuals with neurological conditions such as stroke, traumatic brain injury, Parkinson’s disease, multiple sclerosis, and cerebral palsy, yet they often receive insufficient attention. Disorders like...

Review Article

September 30, 2025

Temporal Tactics: Leveraging Circadian Rhythms in Diabetes Treatment

Varun Chauhan, Deepak Sharma, Saurabh Srivastava

Chronobiol Med. 2025;7(3):128-137.

Diabetes mellitus (DM), a global metabolic disease, is closely associated with circadian rhythms (CRs), and the situation is quite multifaceted for clinicians. Chronobiological knowledge reveals the complex relationship between circadian...

Review Article

September 30, 2025

The Role of Chrononutrition in Global Wellness

Ghizal Fatima

Chronobiol Med. 2025;7(3):138-153.

Chrononutrition aligns dietary patterns with the body’s circadian rhythms, optimizing metabolic processes and promoting health. The human body operates on a 24-hour biological clock, regulating metabolism, hormone secretion, and cellular...

Original Article

September 30, 2025

Can Piperazine-Bearing Fluoro-Benzoxazolone Derivatives Be a Chronotherapeutic Solution for Pain Management?

Ismail Celil Haskologlu, Emine Erdag, Orhan Uludag

Chronobiol Med. 2025;7(3):154-161.

Objective: Chronic pain management remains limited due to the restricted efficacy and adverse effects of conventional analgesics. A chronotherapeutic approach targeting melatonin MT1 and MT2 receptors offers an alternative solution,...

Original Article

September 30, 2025

Feasibility and Preliminary Effectiveness of a Prototype Digital Therapeutic for Insomnia (LUIT-K): A Pilot Study

Solee Han, Seung Pil Pack, Chul-Hyun Cho

Chronobiol Med. 2025;7(3):162-168.

Objective: Insomnia is a prevalent and burdensome condition, with limited access to evidence-based treatments like cognitive behavioral therapy for insomnia (CBT-I). Digital therapeutics offer a promising solution to bridge this...

Original Article

September 30, 2025

Exploring Circadian Oscillation in Human Umbilical Cord–Derived Mesenchymal Stem Cells During Passaging

Hong Thuan Tran, Phuc Gia Nguyen, Ngoc Duong Hoang Bao Nguyen

Chronobiol Med. 2025;7(3):169-176.

Objective: Circadian clock genes regulate key cellular functions and regenerative medicine; however, their role in human umbilical cord–derived mesenchymal stem cells (hUC-MSCs) remains unclear. Methods: We analyzed the expression of core...

Original Article

September 30, 2025

Chronotherapeutic Potential of Withania somnifera Phytocompounds for Narcolepsy Management: An Integrated GC-MS and In Silico Study

Mohammad Azram, Mehakdeep Kaur, Khalid Rasheed, et al.

Chronobiol Med. 2025;7(3):177-191.

Objective: To investigate the chronotherapeutic potential of phytochemicals from Withania somnifera (ashwagandha) leaf extract as histamine H3 receptor (H3R) inhibitors for suppressing H3R overexpression to manage excessive daytime sleepiness (EDS)...

Current Issue: Volume 7(3); Sep 2025

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Copyright © 2025 by Korean Academy of Sleep Medicine. All rights reserved.

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